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Zhou G, Deng X, Tian J, Fazil MHUT, Lakshminarayanan R*, Srinivasan R. SnAP reagents for the synthesis of selenomorpholines and 1,4-selenazepanes and their biological evaluation. Chem Commun (Camb). 2020 Feb;56: 1780-1783.
Parmar A, Lakshminarayanan R, Iyer A, Venkatesh M, Goh ETL, Lloyd DG, Chalasani MLS, Verma NK, Beuerman RW, Madder A, Taylar EJ, Singh I. Highly potent drug like teixobactin analogues against Staphylococcus aureus, MRSA, VRE in vitro and in vivo. J Med Chem. J Med Chem (In press) doi: 10.1021/acs.jmedchem.7b01634.
Parmar A, Iyer A, Prior SH, Lloyd DG, Goh ETL, Vincent CS, Pallag TP, Bachrati Cv Breukink E, Madder A, Lakshminarayanan R, Taylor EJ, Singh I. Design and syntheses of highly potent teixobactin analogues reveals enduracididine not to be essential for lipid II binding and antibacterial activity. Chem. Sci. 2017 Oct,8:8183-8192.
Venkatesh M, Sridhar S, Fazil MHUT, Goh ETL, Orive G, Choong YK, Saravanan R, Beuerman RW, Barkham TMS, Liang Y, Baskaran M, Jhanji V, Loh XJ, Verma NK, Lakshminarayanan R*. Protective action of linear polyethylenimine against Staphylococcus aureus colonization and Exaggerated Inflammation In vitro and In vivo. ACS Infect Dis. 2019 Aug;5: 1411-1422.
Venkatesh M, Barathi VA, Goh ETL, Angaara R, Fazil MHUT, Ng AJY, Aung TT, Liu S, Yang L, Loh XJ, Beuerman RW, Verma NK, Lakshminarayanan R*. Cell selectivity of synthetic and biosynthetic cationic polymer. Antimicrob Agents Chemother. 2017 Sep 22,61(10). pii: e00469-17.
Leung CM, Dhand C, Venkatesh M, Ramalingam R, Lim FP, Barathi VA, Dwivedi N, Orive G, Beuerman RW, Ramakrishna S, Toh YC, Loh XJ, Verma NK, Choong AWC, Lakshminarayanan R*. Wound healing properties of magnesium mineralized antimicrobial nanofiber dressings containing chondroitin sulphate - A comparison between blend and core-shell nanofibers. Biomater Sci. 2020 Jun;8 :3454-3471.
Venkatesh M, Choong ACW, Dhand C, Lim FP, Tun AT, Sriram H, Dwivedi N, Periayah MH, Sridhar S, Fazil MHUT, Goh ETL, Orive G, Beuerman RW, Barkham TMS, Liang ZX, Barathi VA, Ramakrishna S, Chong SJ, Verma NK, Lakshminarayanan R*. Multifunctional antimicrobial nanofiber dressings containing -Polylysine for the eradication of bacterial bioburden and promotion of wound healing in critically colonized wounds. ACS Appl Mater Interfaces. 2020 Apr;12:15989-16005.
Dhand C, Venkatesh M, Barathi VA, Harini S, Bairagi S, Goh ETL, Nandhakumar M, Low KZW, Fazil Mhut, Verma NK, Loh XJ, Liu SP, Beuerman RW, Ramakrishna S, Lakshminarayanan R*. Bio-inspired crosslinking and matrix-drug interactions for advanced wound dressings with long-term antimicrobial activity. Biomaterials. 2017 Sep,138:153-168.
Dhand C, Ong ST, Dwivedi N, Diaz SM, Venugopal JR, Navaneethan B, Fazil Mhut, Liu SP, Seitz V, Wintermanterl E, Beuerma RW, Ramakrishna S, Verma NK, Lakshminarayanan R*. Bio-inspired in situ crosslinking and mineralization of electrospun collagen scaffolds for tissue engineering. Biomaterials. 2016 Oct, 104:323-38.
Obuobi S, Mayandi V, Nor N, Jiansheng B, Lakshminarayanan R, Ee PLR. Nucleic acid peptide nanogels for the treatment of bacterial keratitis. Nanoscale doi: 10.1039/d0nr03095c.
Lakshminarayanan R*, Tan WX, Aung TT, Goh ETL, Muruganantham N, Li J, Chang JYT, Dikshit N, Saraswathi P, Lim RR, Kang TS, Balamuralidhar V, Sukumaran B, Verma CS, Sivaraman J, Chaurasia SS, Liu SP, Beuerman RW. Branched peptide, B2088, disrupts the supramolecular organization of lipopolysaccharides and sensitizes the Gram-negative bacteria. Scientific Reports 2016 May, 6:25905.
Venkatraman A, Murugan E, Lin SJ, Peh GSL, Lakshminarayanan R*, Mehta JS. Effect of osmolytes on in-vitro aggregation properties of peptides derived from TGFBIp. Sci Rep. 2020 Mar;10: 4011.
Venkatraman A, Dutta B, Murugan E, Hao P, Lakshminarayanan R, Chan A, Pervushin K, Sze SK, Mehta JS. Proteomic analysis of amyloid corneal aggregates from TGFBI-H626R Lattice corneal dystrophy patient implicates serine-protease HTRA1 in mutation-specific pathogenesis of TGFBIp. J Proteome Res. 2017 Aug,16:2899-2913.
Anandalakshmi V, Murugan E, Goh ETL, Ting LW, Chaurasia SS, Yamazaki T, Nagashima T, George BL, Peh GSL, Pervushin, Lakshminarayanan R*, Mehta JS. Effect of position specific single point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophic patients. Biochem J. 2017 May,474:1705-1725.
Liu Z, Liow SS, Li Z, Tan MJ, Lai SL, Parikh BH, Kumar K, Gunaratne J, Veluchamy AB, Hunziker W, Laksminarayanan R, Tan CTW, Chee C, Zhao P, Lingam G, Loh XJ, Su X. Dual-function thermogelling polymers as effective endotemponade for retinal detachment repair and reassembly of vitreous-like body in-situ. Nat Biomed Eng. 2019 Aug;3: 598-6102019.
Marawari S, Poulsen A, Shih N, Lakshminarayanan R, Kini M, Johannes CW, Dymock BW, Dawe G. Intranasal delivery of a stapled relaxin-3 mimetic has anxiolytic and antidepressant-like activity. Br J Pharmacol. 2019 Oct;176: 3899-3923.