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Assoc Prof Andrea Low

Assoc Prof Andrea Low

​BmedSci (UK), BMBS (UK), MRCP (UK), FAMS (Rheumatology), MCI

Senior Consultant

Specialty: Rheumatology & Immunology

Clinical Interest: Systemic Sclerosis (Scleroderma)

Conditions Treated by this Doctor:
General Rheumatology, Pulmonary Arterial Hypertension, Pulmonary Hypertension, Systemic Sclerosis (Scleroderma).

Clinical Appointments

  • Senior Consultant Rheumatology & Immunology Singapore General HospitalSingapore General Hospital

Profile

Dr Andrea Low is Senior Consultant in the Department of Rheumatology and Immunology, Singapore General Hospital (SGH). She graduated from the University of Nottingham Medical School, United Kingdom and obtained the Master of Clinical Investigation at the National University of Singapore (NUS). 
 
Dr Low’s research interest is in systemic sclerosis (SSc). In 2007, Dr Low was awarded the Health Manpower Development Plan Fellowship for further training in SSc. She spear-headed the nation-wide collaborative SSc research workgroup comprising Rheumatologists from SGH, National University Health System (NUHS) and Tan Tock Seng Hospital (TTSH). Dr Low helped to establish 5 key department research programs, and provided research mentorship during her term as the Department’s Director of Research from 2008 to 2014. She is also a recipient of the NMRC Transition Award and the Nurturing Clinician Scientist Program in 2012 for her work in SSc.
 
In addition to clinical care and research, Dr Low is actively involved in teaching students and residents, and was awarded the RISE award for outstanding faculty. She believes it is through effective mentorship that future generations of academically-inclined doctors can be nurtured and developed. Dr Low also served as a reviewer for regional and international medical journals.

Education

  • ​Master of Clinical Investigation (MCI, Clinical Research) – National University of Singapore 2011 
  • FAMS (Rheumatology), Academy of Medicine, Singapore 2007 
  • MRCP, Royal College of Physicians, United Kingdom 2002 
  • B.M.B.S., Medicine, University of Nottingham Medical School, United Kingdom 1997 
  • B Med Science, Medicine, University of Nottingham Medical School, United Kingdom 1995

Professional Appointments and Committee Memberships

  • ​Senior Consultant, Department of Rheumatology and Immunology, Singapore General Hospital (SGH) 
  • Visiting Consultant, Combined Pulmonary Hypertension Clinic, National Heart Centre Singapore 
  • Assistant Professor, Duke-NUS Medical School Singapore 
  • Clinical Senior Lecturer, Yong Loo Lin School of Medicine, National University of Singapore 
  • Divisional Research Focus (Immunology and Immunotherapy) - Lead 
  • SGH Research Grant Committee – Member 
  • SGH Research Executive Committee – Member 
  • Systemic Sclerosis Workgroup – Chairperson 
  • Residency Advisory Council, Rheumatology – Member 
  • JCST examination committee for Rheumatology – Member 
  • Rheumatology Senior Residency Performance Evaluation Committee – Chair 
  • Rheumatology Senior Residency Clinical Competency Committee – Chair 
  • Rheumatology Senior Residency Program – Physician Faculty 
  • Reverie Rheumatology Research Fund – Core Group Lead 
  • Immunology Hub Project – Core Group Member 
  • 1st Asia Pacific Pulmonary Hypertension Forum 2017 - Steering Committee Member 
  • Singapore Society of Rheumatologists – Member 
  • Chapter of Rheumatologists, College of Physicians – Member


Awards

  • ​RISE (Residency In Singhealth Excels award), SingHealth, Singapore, Outstanding Faculty Award 2014 
  • NMRC Transition Award 2012 
  • Singapore General Hospital, Medicine Academic Clinical Program, Nurturing Clinician Scientist Program 2012 
  • Singapore Clinician-Investigator, “Predictors of Mortality in Systemic Sclerosis - a Singaporean Cohort”, Singapore Health and Biomedical Congress 2012, Singapore, Silver Award 2012 
  • Singapore Health Quality Service Award, Gold Award (2011), Star Award (2014) 
  • National Research Foundation - Ministry of Health Healthcare Research Scholarship for the Master of Clinical Investigation 2009 
  • Singapore General Hospital, Service Quality Award, Service with a Heart Award 2009 
  • SingHealth Health Manpower Development Program Award for Fellowship in Systemic Sclerosis, 2007 
  • Excellent Service Award (EXSA), Silver Award (2006) 
  • Division of Medicine, International Conference on Evidence-Based Medicine, Singapore General Hospital-Stanford University Hospital Joint Update, Singapore, 1st prize in Meta-analysis Competition, 2003

Research Interests

  • Systemic Sclerosis
  • Imaging
  • Microbiome

Publications

  • Low AHL, Xin X, Law WG, Teng GG, Santosa A, Lim A, Chan G, Ng SC, Thumboo J. Validation of the UCLA Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument 2.0 in English and Chinese-speaking Patients in a Multi-ethnic Singapore Systemic Sclerosis Clin Rheumatol (2017). doi:10.1007/s10067-016-3529-x. Epub 2017 Jan 5. 
  • Santosa A, Tan CS, Teng GG, Fong W, Lim A, Law WG, Chan G, Ng SC, Low AHL. Lung and Gastrointestinal Complications are Leading Causes of Death in SCORE, a Multi-Ethnic Singapore Systemic Sclerosis Cohort. Scand J Rheumatol 2016; 45(6): 499-506 
  • Ng X, Low AHL, Thumboo J. Comparison Of The Charlson Comorbidity Index Derived From Self-Report And Medical Record Review In Asian Patients With Rheumatic Diseases. Rheumatol Int 2015 (in press) Doi: 10.1007/S00296-015-3296-Z 
  • Ali H, Ng KR, Low AHL. A Qualitative Systematic Review of the Prevalence of Coronary Artery Disease in Systemic Sclerosis. Int J Rheum Dis 2015;18:276-286 
  • Shen S, Chan A, Sfikakis P, Low AHL, Detorakis ET, Boboridis KG, Mavrikakis I. B-Cell Targeted Therapy With Rituximab for Thyroid Eye Disease: Closer to the Clinic. Surv Ophthalmol 2012 Dec 17.pii: S0039-6257 (12)00253-6. Doi: 10.1016/ j.survophthal. 2012.10.006 
  • Low AHL, Teng GG, Law WG, Ng SC, Santosa A, Chan G et al. Disease Characteristics of the Singapore Systemic Sclerosis Cohort. Proceedings of Singapore Healthcare 2013; 22(1): 8-14 
  • Ng X, Low AH, Chew LC et al. Disease Patterns of Rheumatology Outpatients Seen in a Tertiary Hospital Serving a Multi-Ethnic, Urban Asian Population in Singapore. Int J Rheum Dis 2013; 16: 273-278 
  • Ng X, Thumboo J, Low AHL. Validation of the Scleroderma Health Assessment Questionnaire and Quality of Life in English and Chinese-Speaking Patients with Systemic Sclerosis. IJRD 2012; 15(3):268-76. Epub 2012 Apr 29 
  • Low AHL,  Wong S, Thumboo J , Ng SC, Lim JY, Ng X, Earnest A, Fong KY. Evaluation of a new multi-parallel line immunoassay for systemic sclerosis-associated antibodies in an Asian population. Rheumatology (Oxford) 2012; 51(8):1465-70. Epub 2012 Apr 6. 
  • Low AH, Lax M, Johnson S, Lee P. Magnetic resonance imaging of the hand in systemic sclerosis. J Rheumatol 2009;36:961-964 
  • Low AH, Johnson S, Lee P. Ethnic influence on disease manifestation and autoantibodies in Chinese-descent patients with systemic sclerosis. J Rheumatol 2009;36:787–93 
  • Low AHL, Lee P. Indirect evidence for the efficacy of methotrexate in diffuse systemic sclerosis J Rheumatol 2008;35:2286 
  • Su JW, Low AH, Tay KH, Sebastian MG, Thumboo J and Sin KYK. Recurrent aortic aneurysms following thoracic aortic stent-graft repair in a patient with Cogan syndrome. J Endovasc Ther 2006;13:779-782. 
  • Low AH, Su JW, Sin KYK, Fong KY, Thumboo J. Cogan’s syndrome with recurrent carotid and aortic aneurysms: a potentially fatal disorder mimicking Marfan syndrome. Scand J Rheumatol 2007;36:71-73 
  • Low AH and Thumboo J. Pathophysiology and diagnosis  of neuropsychiatric SLE. SGH Proceedings 2005;14:203-213. 

Research Trials